One possible issue with USB devices is common ground causing ground loops (both DC and earth).
Low cost USB isolators are now available from a number of sources. We have tested the isolator from Olimex and it works fine with no issues.
http://www.olimex.com/dev/pdf/OTHER/USB-ISO.pdf
When using it an isolated +5V supply is required for KFLOP
Mouser has them in stock for $41 qty 1. They are also available in Europe.
http://www.mouser.com/ProductDetail/Olimex-Ltd/USB-ISO/?qs=hO3QYTFrOd09eOKVRIujMQ%3d%3d